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US Medical Guide
Free Press . . Allopathic and Alternative Health News
Originally Published, Dallas Medical Guide 1991

Condyloma
By Vernie Bodden Jr., M.D.

Anogenital warts from the human papillomavirm (HPV) group were once considered a benign nuisance. However, recent medical journal articles has associated this virus with vulvar cancer and asymtomatic cervical HPV infections.

About 600,000 women seek treatment of anogenital warts each year. The majority are from 20 to 24 years old. Occurrence of Condyloma Acuminata, an HPV infection which is usually sexually transmitted, has increased 500 percent in 20 years.

The dramatic increase is due to several factors: greater sexual activity, a growing population of young adults, more frequent routine pelvic exams, and an increase in awareness of the subtle forms of the disease by patients and physicians.

Traditional risk factors for cervical cancer and HPV infections are similar, including intercourse at an early age and multiple sexual partners. It has been shown that HPV infection in the male partner is an even more significant risk factor for abnormal transformation of cervical and vaginal tissues than the woman's  own sexual behavior.

Initial therapy for anogenital condyloma infection (including the use of topical agents) may fail for several reasons. One is that the incubation period varies from three weeks to eight months and the treatment of only visible lesions may miss incubating areas in which lesions develop later. Lesion surfaces must be thoroughly coated with topical agents for total absorption. Large lesions can rarely be treated adequately with a single application. On the other hand, Condyloma Acuminata has been known to resolve spontaneously or with cursory treatments. This suggests the host immune system is also a controlling factor.

Specific immunologic defeats have been found in certain patients with resistant Condyloma, and illnesses that impair immunity have appeared concomitantly with particularly florid cases of Condyloma Acuminata. Vaccines prepared from the patient's lesion and interferon have been used, but results have been far from promising.

Physicians usually discuss the infection and its treatment with the patient before beginning therapy to prevent later misunderstandings. A patient with Condyloma Acuminata should be prepared to undergo several treatment sessions for eradication, if necessary.

The treatments are varied and depend on the number and location of the lesions. Podophyllin, a topical agent that is available, minimally painful, and easy to use, is generally the first treatment for external Condyloma. Treatment is repeated every one to two weeks.

If individual lesions have not responded after three or four applications, Tricholroacetic Acid (TCA) or Cryotherapy can be used. If new lesions continue to arise, it is best to treat affected areas and surrounding surfaces with CO2 laser photo coagulation.

5-Flurouracil -- an antimetabolite (available in five percent topical cream) can be used as primary treatment for intravaginal inflammation. Major side effects are erosive vulvitis and urethritis, generally prevented by application of zinc oxide cream or petrolatum to the vulva and urethral opening after insertion of the the cream and tampon and after its removal and cleansing of the vulva the following morning.

Laser therapy is available for large warty lesions that don't respond to more conservative measures. Care should be taken to relcaleitraut before proceeding with laser destruction.

We have no way of preventing HPV infection. but to reduce the risk of malignancy annual Pap Smears, careful inspection of the anogenital organs in the female, and clinical examinations of the anogenital areas in the male are recommended for early detection of Condyloma. Once detected these growths should be removed.

©1991, 2008 US Medical Guide, Susan and Terry Turner

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